Ketogenic Diets May Protect Against Oxidative Damage

mouse 1In today’s post, I’ll review a recent study proposing a possible mechanism for the benefits of a ketogenic diet. This post builds on my previous post about epigenetics.

In the research paper “Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor,” researchers investigate the role of β-Hydroxybutyrate (βOHB) in preventing damage by oxidative stress. βOHB is a product of fat oxidation and serves as the major source of energy during prolonged exercise, under fasting conditions, or when following a ketogenic diet.  Continue reading